Particle analyser

Anton Paar

Litesizer™ 500

Materials characterization

Characterization of nano- and microparticles in dispersions and solutions.

Determination of particle size, zeta potential, and molecular mass by measuring dynamic light scattering (DLS), electrophoretic light scattering (ELS), and static light scattering (SLS).

Litesizer™ 500 is also able to perform a straightforward measurement of the sample’s refractive index.

General specifications

Temperature control range: 0–90 °C

Light source: laser / 40 mW, 658 nm

 

Particle size specifications

Measuring range:  0.3 nm – 10 μm (particle diameter)

Sensitivity:

• min. conc. (protein) 0.1 mg/mL (lysozyme)
• min. conc. (polymer) 1 µg/mL (polystyrene latex)

Accuracy: better than +/-2 % on certified reference material

Repeatability: better than +/-2 % on certified reference material

Minimum sample volume: 12 µL

Measurement angles: 15°, 90°, 175°

 

Zeta potential specifications

Measuring range: -600 to +600 mV

Mobility: 10-11 m²/V.s to 2 x 10-7 m²/V.s

Size range: 3.8 nm – 100 µm

Sensitivity: 1 mg/mL (lysozyme)

Maximum sample concentration: 40 % w/v

Sample volume: 350 µL

Maximum sample conductivity: 200 mS/cm

 

Molecular mass specifications

Measuring range (mass): 980 Da – 20 MDa

Measuring range (particle size): up to 40 nm (diameter)

Sensitivity: 0.1 mg/mL (lysozyme)

Accuracy: +/-10 %

Repeatability: +/-5 %

Measurement angle: 90°

 

Transmittance specifications

Size range: no limit

Measuring time: 10 s

Minimum sample volume: 15 µL

 

Refractive index specifications

Measuring range: 1.28 to 1.50

Accuracy: +/-0.5 %

Temperature range: 0 °C to 90 °C

Wavelength: 658 nm

Minimum sample volume: 1 mL

Wetted parts: quartz, glass